EyeWorld Asia-Pacific December 2019 Issue

| 1 Clareon ® - a new standard for IOL clarity Larry Li Clareon ® IHDWXUHV DQ DGYDQFHG Ζ2/ GHVLJQ DQG SURYLGHV XQVXUSDVVHG FODULW\ RI D WUXO\ SULVWLQH SUHPLXP Ζ2/ WKXV VHWWLQJ D QHZ VWDQGDUG IRU Ζ2/ FODULW\ &ODUHRQ ® constitutes a precision edge design that PLQLPL]HV JODUH DQG G\VSKRWRSVLD The precision design of Clareon ® is a result of the new cryo-milling process, which incorporates D SURSULHWDU\ FXUYDWXUH RQ WKH VLGH WR PLQLPL]H HGJH JODUH DQG SRVWHULRU FDSVXODU RSDFLȴFDWLRQ 3&2 H[SODLQHG 'U /DUU\ /L +HDG RI 50$ $OFRQ $VLD 3DFLȴF )URP D ELRPHFKDQLFDO SHUVSHFWLYH &ODUHRQ ® incorporates 67$%/()25&( ® haptics to maintain optical stability during FRPSUHVVLRQ DQG DOORZV UDSLG DQG FRQWUROOHG XQIROGLQJ RI WKH Ζ2/ due to lower glass transition temperature and with the help of AutonoMe ® delivery system. )LJXUH A study that compared Clareon ® with single- piece AcrySof ® Ζ2/ HQ9LVWD ® 7(&1Ζ6 ® , and 9LYLQH[ ® revealed that Clareon ® and AcrySof ® VKRZ VLJQLȴFDQWO\ ORZHU D[LDO GLVSODFHPHQW than others. 7 Clareon ® also demonstrates minimal glare response compared to leading competitors and provides unsurpassed clarity ZLWK ORZHVW OHYHO RI VXUIDFH KD]H VXEVXUIDFH QDQRJOLVWHQLQJV 661*V DQG JOLVWHQLQJV WKDQ RWKHU SUHPLXP PRQRIRFDO Ζ2/V Figure 1: Clareon ® STABLEFORCE ® haptics maintain optical stability when compressed to 9 mm Clareon ® LV D QH[W JHQHUDWLRQ DGYDQFHG GHVLJQ PRQRIRFDO Ζ2/ PDGH IURP K\GURSKRELF DFU\OLF ZKLFK SURYLGHV XQVXUSDVVHG RSWLFDO FODULW\ RI D WUXO\ SULVWLQH SUHPLXP Ζ2/ R΍HULQJ ORZHVW OHYHO RI VXUIDFH KD]H VXEVXUIDFH nanoglistenings, and glistenings, FRPSDUHG WR RWKHU SUHPLXP PRQRIRFDO Ζ2/V Clinical experience with Clareon ® Autonome ® Fook Meng Cheong Clareon ® Autonome ® LV WKH ȴUVW DQG RQO\ DXWRPDWHG GLVSRVDEOH DQG SUHORDGHG Ζ2/ GHOLYHU\ V\VWHP GULYHQ E\ DQ LQQRYDWLYH &2 SRZHUHG delivery mechanism. 8 ΖW LV HDV\ DQG LQWXLWLYH DQG DOORZV VLQJOH KDQGHG injection with a responsive speed control lever and comfortable ergonomic hand positions. ΖW SURWHFWV LQFLVLRQV ZLWK LWV SURSULHWDU\ GHSWK JXDUG DQG SURYLGHV IXOO Ζ2/ YLVLELOLW\ GXULQJ GHOLYHU\ ZLWK D PP QR]]OH WLS OHQJWK )LJXUH The Clareon ® Autonome ® delivery system is prepared in three simple VWHSV ZLWK ZHOO GHȴQHG HQG SRLQWV 7KH ȴUVW VWHS LQYROYHV ȴOOLQJ WKH FKDPEHU ZLWK RSKWKDOPLF YLVFRVXUJLFDO GHYLFHV 29' WR WKH WLS RI WKH QR]]OH WR HQVXUH D ȴ[HG FROXPQ RI 29' LQ HYHU\ FDVH WKH VHFRQG step consists of removing the lock-out assembly and the third step LQYROYHV SUHVVLQJ GRZQ IXOO\ RQ WKH OHYHU WR DGYDQFH WKH Ζ2/ WR LWV SUH GHOLYHU\ SRVLWLRQ 7KH DXWRPDWHG Ζ2/ GHOLYHU\ LV WKHQ LQLWLDWHG and controlled by the surgeon with the speed control lever. Ȋ:LWK ZHOO GHȴQHG HQG SRLQWV LQ WKH SUHSDUDWRU\ VWDJH DQG WKH DXWRPDWHG DGYDQFHPHQW RI WKH SOXQJHU WKH YROXPH RI 29' DQG VSHHG RI SOXQJHU DGYDQFHPHQW DUH VWDQGDUGL]HG LQ HYHU\ FDVH +DYLQJ WKH VDPH YROXPH RI 29' DQG WKH VDPH VSHHG RI SOXQJHU DGYDQFHPHQW FRQWULEXWHV WR FRQVLVWHQW IROGHG FRQȴJXUDWLRQV RI WKH Ζ2/Vȋ H[SODLQHG 'U )RRN 0HQJ &KHRQJ 'U &KHRQJ SUHVHQWHG DQ REVHUYDWLRQDO DXGLW RI KLV LQLWLDO H[SHULHQFH with the Clareon ® Autonome ® delivery system comprising of SRROHG GDWD IURP VLWHV LQYROYLQJ H\HV RI SDWLHQWV DQG IROORZHG IRU PRQWK 7KHUH was minimal corneal incision wound stretch for 2.2 mm incisions; no wound stretch for PP LQFLVLRQV DQG QR]]OH WLS LQWHJULW\ ZDV maintained in all cases without post-operative injector tip damage. With regards to unaided distance visual acuities, all eyes could see 20/40 RU EHWWHU DQG RI ideal eyes for non-toric Ζ2/V EDVHG RQ WKH %DUUHWW 7RULF FDOFXODWRU could see 20/20 and FRXOG VHH RU EHWWHU ΖQ DVVHVVLQJ refractive predictability at PRQWK IROORZ XS RI H\HV ZHUH ZLWKLQ ' RI SUHGLFWHG UHIUDFWLRQ ΖQ H\HV WKDW WKH %DUUHWW 7RULF FDOFXODWRU UHFRPPHQGHG D QRQ WRULF Ζ2/ LPSODQW RI H\HV ZHUH ZLWKLQ ' RI SUHGLFWHG UHIUDFWLRQ ΖQ P\ H[SHULHQFH WKH IHHGEDFN UHFHLYHG IURP VXUJHRQV ZDV H[WUHPHO\ VDWLVIDFWRU\ UHJDUGLQJ WKH VLPSOLFLW\ RI SUHSDUDWLRQ HDVH RI implantation, responsiveness and intuitiveness of using the Clareon ® Autonome ® delivery system," added Dr. Cheong. Clareon ® AutonoMe ® LV DQ HDV\ DQG LQWXLWLYH DXWRPDWHG SUHORDGHG Ζ2/ GHOLYHU\ V\VWHP WKDW DOORZV VLQJOH KDQGHG Ζ2/ LQMHFWLRQ ZLWK UHVSRQVLYH VSHHG FRQWURO OHYHU DQG FRPIRUWDEOH HUJRQRPLF KDQG SRVLWLRQV Zhao Ping Shenyang AIER Eye Hospital China VilavunPuangsricharern Chulalongkorn University Hospital Thailand Abhijeet Desai Sohum Eye Care Centre India Krishna Prasad MM Joshi Eye Institute India Zhang Chun Xiamen Eye Center Xiamen University China Figure 2: Advantages of Clareon ® Autonome ® Delivery System 3KRWRJUDSKV FRXUWHV\ RI 'U &KHRQJ

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